CYSTIC FIBROSIS

I have an unusual genetic disorder that seems to resemble cystic fibrosis.  After struggling with this for the past forty three years, I have decided that it has given me insights into cystic fibrosis.  I have read the research on cystic fibrosis.  The main problem in CF is poor utilization of the chloride ion. Chloride is one of our electrolytes.  Electrolytes are essential for life.

I believe that the poor utilization of chloride results in the flawed metabolism of the fat-soluble vitamins:  A, D,E, and K.

Vitamin A is important for normal lung development.  The flawed metabolism of vitamin A results in lung damage.

Vitamin K is important for blood clotting.  The flawed metabolism of vitamin K results in bleeding.

The flawed metabolism of vitamin E seems to result in depression.

The flawed metabolism of vitamin D results in peripheral neuropathy.

Chloride is essential for breathing.  Of course this relates to lung development.  I do not believe that anyone with CF should take vitamin A or beta carotene supplements.  A great deal of zinc is also required for metabolizing vitamin A and beta carotene.  Beta carotene especially drains the body of zinc.  Simply eating fruits and vegetables and also eating pre-metabolized vitamin A, such as is found in eggs, milk, yogurt, and cheese along with pancreatin for absorption might supply sufficient vitamin A. Taking more of the vitamin in food or supplements than the body can metabolize simply damages the lungs.

People with CF should not take vitamin K supplements.  Just eating the green vegetables might be sufficient.  Certainly intravenous vitamin K should not be given.  Intravenous chloride might help. Intravenous potassium chloride, sodium chloride, magnesium chloride, etc. might help.

Vitamin E supplements should not be taken.

Peripheral neuropathy is complicated.  Besides the chloride, chromium deficiency and magnesium deficiency are involved.  Intravenous chromium will completely eliminate the pain and loss of proprioception.  After this treatment, oral supplements of pancreatic enzymes and chromium can maintain the proprioception and freedom from pain.   Magnesium deficiency results in the numbness.  Magnesium is difficult to absorb.  It must be taken with pancreatic enzymes and whole grains.  Sugar drains magnesium out of the system.  Also alcohol and other substances drain magnesium out of the system.  Two much magnesium will just result in diarrhea which will result in magnesium loss.  The supplement Betaine hydrochloride (basically hydrochloric acid) will supply chloride, but it can also provide too much acid.  A premetabolized form of vitamin D, such as Rocaltrol is helpful.